n-acetylcysteine raises glutathione levels Effects of N-acetylcysteine, oral (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study N-Acetylcysteine (NAC): Impacts on Human

Increasing GSH and/or GSH-dependent antioxidant enzymes directly Many studies have concentrated on the direct effects of synthetic drugs on GSH and GSH-dependent antioxidant enzymes in damaged myocardium without further mechanistic investigations

34 reported that ROS may have a secondary role in Con A-induced hepatitis because hepatic oxidative stress was increased 12 h after Con A injection but not earlier

Exp Neurol (2003) 184(2):9971002

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Analysis of clinical secondary endpoints Fishers exact test was used to compare categorical variables (as short-term neonatal morbidity) between NAC- and placebo arms