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Figure 4 Inhibitory Effects on Key Enzymes in l-2HG Pathway The finding that at higher iron concentrations less glutarate and more l-2HG accumulated, while the combined concentration of glutarate plus l-2HG was highest at the lowest iron concentration indicated bottlenecks
In neurodegenerative diseases like Alzheimers and Parkinsons, antioxidants may help protect neurons from oxidative damage and slow disease progression [199]
doi: 10.1016/j.fct.2022.113550
A., Furukawa K., Markesbery W
Wiley, A., Katsaros, D., Fracchioli, S
