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[DOI] [PubMed] [Google Scholar] 44.Dolan ME, Frydman B, Thompson CB, et al

Similar content being viewed by others Introduction Oxidative stress accompanies a wide variety of diseases 1 , including sickle cell disease (SCD), HIV/AIDS, and rheumatoid arthritis, and antioxidant therapy is emerging as a pharmacological strategy for treating diseases in which oxidative stress is known or suspected to be elevated 2

On the contrary, administration of different NAD + precursors to boost intracellular NAD + levels increased Ca 2+ mobilization, promoted cell proliferation and IL-2 release in response to mitogens, thereby upregulating activated T cell functions [115]

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doi: 10.1007/s43032-022-01038-2 51 SahebkarAKatsikiNWardNReinerZ