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Experimental evidence supporting or refuting the operation of one or more of the postulated mechanisms is sorely lacking

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A 2011 systematic review of clinical data suggested that citicoline could hasten the resorption of cerebral edema and improve the recovery of consciousness and neurologic disorders in severe TBI cases (classified by Glasgow Coma Scale [GCS] scores of 8) (5)

However, more specifically a calcium deficiency in men could cause infertility issues as it helps the production of sperm