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It also modulates AMPK/mTOR signaling, influencing cardiomyocyte metabolism and autophagy, and thus CH regulation (202, 228)

Measuring 3-hydroxyisovaleric acid has been shown to be the most sensitive marker of biotin deficiency [8]

We analyzed hepatocyte growth factor (HGF), which protects various organ systems, including the heart, against the effects of oxidative stress [34,35,36]

The experiments were approved by the Animal Ethics Committee of NJUCM (Application Number: 202203A069) on 8th Mar, 2022

6.3 Alcohol Alcoholic liver disease patients have low hepatic and plasma GSH levels due to multiple mechanisms such as oxidative stress, nutritional deficiency and abnormalities in the methionine metabolic pathway that impairs cysteine availability [164166]