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7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects
Dawes P, Cruickshanks KJ, Marsden A, Moore DR, Munro KJ
2 Figure 1

When you take a medication regularly, each new dose adds to what remains from previous doses

(3) While this is a small research sample, another source also confirmed an increase skin thickness, hydration and elasticity
