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2000) Boswellic acids , particularly 11-keto--boswellic acid (KBA) and acetyl-11-keto--boswellic acid (AKBA), have low oral bioavailability due to poor water solubility and first-pass metabolism

Their important antioxidant function was shown in various places and cell structures: GPx1 is ubiquitous in the cytosol and mitochondria, GPx2 in the intestinal epithelium, and GPx3 in the plasma
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The levels of ROS in VECs were decreased

The ensuing broad activation of ion pumps, coupled with elevated metabolism and oxygen demand, may cause brain tissue hypoxia
