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A subsequent study identified the compound N-(4-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)phenyl)acetamide as a notable SARM1 inhibitor, which demonstrated significant efficacy in a mouse model of CIPN (Fig

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Metabolic glycoengineering techniques can be used to introduce various chemical groups into the cellular glycoconjugate chain through the treatment of nonnatural monosaccharides, which can artificially generate bioorthologous groups on tumors as artificial receptor targets for selective targeting in complex environments [143,144]