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NSAIDs and Gastric Mucosa Damage Inhibition of prostaglandin synthesis leading to mucosal damage Increased risk of gastric ulcers and bleeding Potential for black stools due to gastrointestinal bleeding Anticoagulants and Bleeding Risk Anticoagulants help prevent blood clots but raise the risk of bleeding
The most common starting point is 250 mcg twice daily, totaling 500 mcg per day
Malachi Chaney, Hillcrest, Jr., 2011.5
2016;12:e1005390
AOD 9604 efficacy in clinical trials was modest at best
