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If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy

Ecotoxicol Environ Saf 281:116645 Akhigbe TM, Fidelis FB, Adekunle AO, Ashonibare VJ, Akorede BA, Shuaibu MS, Hassan SA, Adegbola CA, Ashonibare PJ, Oladapo OM, Adeogun AE, Bamidele SG, Oyedokun PA, Mukolokota M, Kukoyi OS, Oladipo AA, Adelowo OE, Akangbe MD, Hughes JR, Ricken AM, Culty M, Avellar MCW, Akhigbe RE (2025) Does coenzyme Q10 improve semen quality and circulating testosterone level

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[4] Natural Cosmeceutical Research Board