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The gut microbial metabolite butyrate alleviates IL-1-induced mitochondrial dysfunction and oxidative stress in pancreatic islets

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[62] Ingestion of alcohol can initiate systemic pro-inflammatory changes through two intestinal routes: (1) altering intestinal microbiota composition (dysbiosis), which increases lipopolysaccharide (LPS) release, and (2) degrading intestinal mucosal barrier integrity thus allowing LPS to enter the circulatory system

Vitamin B 12 may also have a role in attenuating neurological deterioration after surgery for DCM