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Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure

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Therapeutic interventions have shown promise in ameliorating these effects

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Therefore, metabolic reprogramming not only increases intracellular drug concentration but also elevates ROS level that in turn promotes antibiotic killing (Fig

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ACh functions both within the brain, where it is involved in cognitive processes such as concentration, learning, and memory, and within the peripheral nervous system where it is a vital signaling chemical at the junction between nerves and muscles

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Net-beneficial preferred terms uric acid lowered -0.69/-0.92/-0.95 mg/dL (about 73% mediated by weight loss)

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