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Notably, omniligase-1, a broad-specificity ligase engineered from subtilisin BPN, was successfully used to synthesize exenatide, and peptiligase has been applied for gram-scale quantities of therapeutic peptides such as thymosin-1, exenatide, and the kalata B1 variant T20K

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A randomized, double-blind, placebo-controlled, phase III trial of erlotinib with or without a c-Met inhibitor tivantinib (ARQ 197) in Asian patients with previously treated stage IIIB/IV nonsquamous nonsmall-cell lung cancer harboring wild-type epidermal growth factor receptor (ATTENTION study)

This imbalance leads to an elevation in markers of oxidative damage such as lipid peroxidation, protein carbonylation, and DNA damage

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