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Whereas other globins use cytochrome b 5 reductase 3, the reaction of neuroglobin with this enzyme is slower than that of hemoglobin by a factor of 100, raising the question as to whether other reductases serve neuroglobin

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In particular, fibrin has a direct beneficial effect on cultured islets, including islet morphology, insulin secretion, and islet angiogenesis (81)