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Description
In SCA3, ASOs have been used either to decrease overall ATXN3 levels or to generate a truncated ATXN3 which lacks the polyQ expansion [280, 281]
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Are Peptides Easy to administer
Potential Long-Term Risks Although AOD-9604 does not increase IGF-1 levels, there are concerns about its long-term metabolic effects, including: Unknown impact on fat metabolism regulation Since AOD-9604 alters fat-burning pathways, researchers are still investigating whether prolonged use could affect natural fat metabolism
Schweikhard, L
