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Similarly, prostaglandin E2 (PGE2) can promote ferroptosis in tumor-infiltrating CD8 + T cells by interfering with the IL-2 signaling pathway (141)

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doi: 10.1038/jid.2009.221 23 UrsellLKMetcalfJLParfreyLWKnightR

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Additionally, thiols are chemically reactive and prone to oxidation, particularly in aqueous and oxygenated environments, leading to the formation of various oxidation products, including disulfides (which may be inactive), such as in the case of NAC (Primas et al., 2023

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