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In subsequent years, the Honolulu Heart Study (1976) (715) and Framingham Heart Study (1977) (559) both reported that many CVD patients had low HDL-C levels

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44 Injury signals from the evolving plaque trigger the expression of adhesion proteins on endothelial cells and the production of soluble chemotactic proteins from resident macrophages, which promotes the attachment and infiltration of additional macrophages, lymphocytes, and platelets to the plaque

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