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[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Vigushin D.M., Mirsaidi N., Brooke G., Sun C., Pace P., Inman L., Moody C., Coombes R.C

Ferri 2015

In terms of clinical significance, personalized administration of probiotics with known strain types, dosage composition, defined impact on individual autochthonous microbiota, improved data on endocrine regulation, and hormonal values are necessary to determine conclusive clinical relevance in women with PCOS (70)

This is especially relevant for peptides that are hydrophobic, basic, prone to aggregation, or known to form cloudy or gel like solutions during standard reconstitution

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