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however, they may cause excessive perspiration as an undesirable consequence [40]

10.1016/j.stem.2018.11.001 125 SchbelerD

For example, pro-inflammatory factors (e.g., tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and interleukin-6 (IL-6), etc.) (9295), inflammatory mediators (e.g., prostaglandins (PGE2), nuclear kappa factor B (NF-B), and cyclooxygenase-2 (COX-2), etc.) (96, 97), and oxidative stress-associated molecules (e.g., ROS, RNS, and MDA, etc.) are upregulated after stroke (98, 99)

The disease has been seen primarily in Holsteins with a few cases in Shorthorns and Jamaican cattle

Weber K., Bosch A., Bhler M., et al., Aerosols of Synthetic Amorphous Silica Do Not Induce Fibrosis in Lungs After Inhalation: Pathology Working Group Review of Histopathological Specimens From a Subchronic 13Week Inhalation Toxicity Study in Rats, Toxicology Research and Application 2 (2018): 2397847318805273
