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A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

Gain in MET copy number is present in almost 16% of the HNSCC patients and associated with an increased c-MET expression and poorer outcome [87]

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Vitamin B12 plays a vital role in brain function and the production of DNA and red blood cells

The primary end point of the trial was the progression of the disease until patients needed treatment with L-DOPA or a dopamine agonist compared to control, and results showed that patients who received the antioxidants combination extended the time when L-DOPA became necessary by 2.5 years, suggesting that the progression of PD may be slowed by the administration of vitamin C and E