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J Biol Chem 275(51):4051740528
That does not mean they do nothing
In some cases, adding folate improves neurologic symptoms when B12 alone does not
Carmona A, Roudeau S, Ortega R (2021) Molecular mechanisms of environmental metal neurotoxicity: a focus on the interactions of metals with synapse structure and function
Cost considerations also favor micro-dosing for long-term management
