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Report of the panel on dietary reference values of the committee on medical aspects of food policy

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They are not intended to represent clinical evidence in humans, and 5-Amino-1MQ has not been approved by the FDA, EMA, or any other regulatory authority for any indication

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Some evidence indeed suggests that the presence of PEW and inflammation may justify the observed reverse association between homocysteine and clinical outcome in CKD and ESRD patients [34,35,36,37]