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10.1093/cid/ciu392 [DOI] [PMC free article] [PubMed] [Google Scholar] Manyi-Loh C, Mamphweli S, Meyer E, Okoh A

Local TrkB signaling: themes in development and neural plasticity

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The within-individual variation from dose to dose in oral semaglutide bioavailability was relatively high, but as a result of daily dosing and a long plasma half-life (1 week), the variability of semaglutide exposure at steady state was considerably reduced

This would provide a more accurate depiction of the action of MET inhibitors in vivo, and subsequently their likely clinical benefit