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Finally, Hemarina- M101 is an extracellular haemoglobin derived from a marine invertebrate formulated into an oxygen carrier called Hemoxycarrier used in cold storage solutions to deliver oxygen (174)

However, the last step of AsA synthesis is linked with a mitochondrial-localized enzyme called l-GalL dehydrogenase (l-GalLDH, EC 1.3.2.3) (Bartoli et al., 2000)

Therefore, the restoration of gut health and immune regulatory functions by probiotics may provide novel insights for the prevention and treatment of hypothyroidism

This work was co-funded by FEDER funds through the COMPETE/QREN, FSE/POPH, and POCICOMPETE 2020 (POCI-01-0145-FEDER-007491) funds

doi: 10.1016/j.freeradbiomed.2024.12.048