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They also improve cachexiarelated anorexia by stimulating ghrelin receptors [78]
Activation of CB1R not only regulates cAMP levels via Gs and Gi proteins, but also modulates intracellular Ca2 + concentration through Gq proteins
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In: ClarkCMTrajanowskiJQ, editors
Gq activates phospholipase C (PLC), a lipase enzyme that cleaves the signaling phosphoinositide lipids (PIP2) of the plasma membrane, generating several key 2nd messengers IP3 and diacylglycerol
