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It was reported to prevent human microvascular endothelial cells from high glucose-induced oxidative stress, aortic fibrosis and inflammation in diabetes by inhibiting the binding of Keap1 to Nrf2 [147, 148]

All the reagents were administered intravenously at a unanimous dose of 20 mg/kg of TPCA-1 and 1.0 mg/kg of siG every other day

Gao, Y., Zhao, C., Liu, X., Zhang, M., and Leung, L

In mothers, elevated hCG levels may disrupt dopamine and serotonin signaling, contributing to mood disorders, memory deficits, and anxiety, while also being linked to gestational hypertension and pre-eclampsia, which can impair cerebral perfusion and promote neuroinflammation [135]

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