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The journal of steroid biochemistry and molecular biology , 190 , 8898

Another study showed that sorafenib resistance was mediated by endoplasmic reticulum stress (ERS) and subsequent PKM2 accumulation
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In the future, combining classic ferroptosis inhibitors such as Fer-1 and Lip-1 or emerging drugs with traditional anti-inflammatory drugs to achieve dual protection by simultaneously inhibiting inflammation and lipid peroxidation might be a new strategy to effectively delay OA progression
