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One study found that rats receiving EGCG (with sildenafil) showed significantly increased eNOS expression and cyclic guanosine monophosphate levels in cavernosal tissues, with reduced MDA (lipid peroxidation marker) levels, compared to untreated groups (258)

[DOI] [PubMed] [Google Scholar] 50.Nemzer BV, Rodriguez LC, Hammond L, Disilvestro R, Hunter JM, Pietrzkowski Z

The observed reduction in seminiferous tubule diameter in the PRP/PC group can be interpreted in the context of ongoing tissue remodeling, where residual degenerative changes and early fibrotic processes may contribute to tubular compaction

PMID 19664690

SARMs that are more selective in their action could potentially be used for a broader range of clinical indications other than the relatively limited legitimate uses that anabolic steroids are currently approved for