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Acknowledgements Our research was supported by the National Institutes of Health through The University of Texas MD Anderson Cancer Centers Support Grant CA016672, National Cancer Institute grant RO1CA 089266 (MHL), Directed Medical Research Programs Department of Defense Synergistic Idea Development Award BC062166 (SCY, MHL), the Susan G

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The single nucleotide polymorphisms (SNPs) of the ABCG5/G8 gene have been found to be associated with insulin resistance and T2DM in Turks [98] and Taiwanese [99]

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Some natural cell membranes such as exosomes without any functionalization have ability to cross the BBB