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Up to now, SIRT5/7 and HDAC1-3 of HDAC class III have been reported to function as a desuccinylase in addition to their deacetylation activity [22,23,24]

Challenges and opportunities in NASH drug development

Furthermore, a study by Lateef and Akintubosun [83] indicated that sleep deprivation is associated with reduced testosterone levels and augmented oxidative damage in sperm cells

Importantly, it was established that Klotho is involved in type 2 diabetes and insulin resistance

J Controll Rel 301:176189 Zelba H, McQueeney A, Rabsteyn A, Bartsch O, Kyzirakos C, Kayser S, Harter J, Latzer P, Hadaschik D et al (2022) Adjuvant treatment for breast cancer patients using individualized neoantigen peptide vaccinationa retrospective observation
