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Results Of the 1,283 screened individuals, 223 were enrolled in one of the two cohorts: Cohort 1 included 101 (45%) individuals with negative RT-PCR results who cohabited with individuals infected with SARS-CoV-2, and Cohort 2 included 122 (55%) recently infected individuals who were asymptomatic or had mild pneumonia

Biochim Biophys Acta 1822(9):13741386

de Lemos, J

Although many of the VacA-mediated effects either directly or indirectly result from membrane binding and pore formation, VacA also enters the cytosol, subsequently accumulates in the mitochondrial inner membrane, and activates endogenous mitochondrial channels, thereby inducing apoptosis (105, 212, 329, 691)

May 12, 2022