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Description
For example, in models of CRPC, upregulation of IGF-2 via the transcription factor GATA2 strongly contributed to chemotherapy resistance after docetaxel and cabazitaxel treatment, by activating numerous downstream kinases including IGF-1R and INSR
PloS One (2016) 11(12):e0168907
Multi-pathway peptides influence several simultaneously
Sixty-two women were equally divided into two groups
Bioavailability ranges from 60-75% depending on injection technique, site selection, and individual tissue perfusion
